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Apolipoprotein E mediates uptake of Sf 100-400 hypertriglyceridemic very low density lipoproteins by the low density lipoprotein receptor pathway in normal human fibroblasts.

作者信息

Gianturco S H, Gotto A M, Hwang S L, Karlin J B, Lin A H, Prasad S C, Bradley W A

出版信息

J Biol Chem. 1983 Apr 10;258(7):4526-33.

PMID:6300089
Abstract
摘要

相似文献

1
Apolipoprotein E mediates uptake of Sf 100-400 hypertriglyceridemic very low density lipoproteins by the low density lipoprotein receptor pathway in normal human fibroblasts.载脂蛋白E通过低密度脂蛋白受体途径介导正常人成纤维细胞摄取Sf 100 - 400高甘油三酯血症极低密度脂蛋白。
J Biol Chem. 1983 Apr 10;258(7):4526-33.
2
Low-density lipoprotein receptor binding determinants switch from apolipoprotein E to apolipoprotein B during conversion of hypertriglyceridemic very-low-density lipoprotein to low-density lipoproteins.在高甘油三酯血症的极低密度脂蛋白转化为低密度脂蛋白的过程中，低密度脂蛋白受体结合决定簇从载脂蛋白E转换为载脂蛋白B。
J Biol Chem. 1984 Dec 10;259(23):14728-35.
3
Receptor-mediated uptake of hypertriglyceridemic very low density lipoproteins by normal human fibroblasts.正常人成纤维细胞对高甘油三酯血症极低密度脂蛋白的受体介导摄取。
J Lipid Res. 1982 Sep;23(7):984-93.
4
The receptor-binding domain of human apolipoprotein E. Binding of apolipoprotein E fragments.人载脂蛋白E的受体结合结构域。载脂蛋白E片段的结合
J Biol Chem. 1983 Oct 25;258(20):12341-7.
5
Apolipoprotein-E degradation in human very low density lipoproteins by plasma protease(s): chemical and biological consequences.
Biochem Biophys Res Commun. 1982 Dec 31;109(4):1360-7. doi: 10.1016/0006-291x(82)91927-1.
6
Receptor binding of cholesterol-induced high-density lipoproteins containing predominantly apoprotein E to cultured fibroblasts with mutations at the low-density lipoprotein receptor locus.胆固醇诱导的主要含载脂蛋白E的高密度脂蛋白与低密度脂蛋白受体位点发生突变的培养成纤维细胞的受体结合。
Biochemistry. 1980 Sep 2;19(18):4359-65. doi: 10.1021/bi00559a032.
7
Low-density lipoproteins modified by lipid transfer protein have altered biological activity.经脂质转运蛋白修饰的低密度脂蛋白具有改变的生物学活性。
Biochim Biophys Acta. 1984 Sep 12;795(2):314-25. doi: 10.1016/0005-2760(84)90081-x.
8
Familial dysbetalipoproteinemia. Abnormal binding of mutant apoprotein E to low density lipoprotein receptors of human fibroblasts and membranes from liver and adrenal of rats, rabbits, and cows.家族性异常β脂蛋白血症。突变载脂蛋白E与人成纤维细胞以及大鼠、兔子和奶牛肝脏及肾上腺膜的低密度脂蛋白受体的异常结合。
J Clin Invest. 1981 Oct;68(4):1075-85. doi: 10.1172/jci110330.
9
Roles of apolipoproteins B and E in the cellular binding of very low density lipoproteins.载脂蛋白B和E在极低密度脂蛋白细胞结合中的作用。
J Clin Invest. 1985 Feb;75(2):361-9. doi: 10.1172/JCI111708.
10
Low density lipoprotein receptors in cultured skin fibroblasts from psoriasis patients.
Clin Genet. 1984 Mar;25(3):230-41. doi: 10.1111/j.1399-0004.1984.tb01983.x.

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Two apolipoprotein E mimetic peptides with similar cholesterol reducing properties exhibit differential atheroprotective effects in LDL-R null mice.两种具有相似降胆固醇特性的载脂蛋白 E 模拟肽在 LDL-R 基因敲除小鼠中表现出不同的抗动脉粥样硬化作用。
Atherosclerosis. 2013 Mar;227(1):58-64. doi: 10.1016/j.atherosclerosis.2012.10.064. Epub 2012 Nov 2.
2
Function and comorbidities of apolipoprotein e in Alzheimer's disease.载脂蛋白E在阿尔茨海默病中的功能及共病情况
Int J Alzheimers Dis. 2011 Apr 5;2011:974361. doi: 10.4061/2011/974361.
3
The vascular contribution to Alzheimer's disease.
血管因素与阿尔茨海默病。
Clin Sci (Lond). 2010 Aug 5;119(10):407-21. doi: 10.1042/CS20100094.
4
Insight on the molecular envelope of lipid-bound apolipoprotein E from electron paramagnetic resonance spectroscopy.利用电子顺磁共振波谱技术对脂质结合载脂蛋白E分子包膜的见解。
J Mol Biol. 2009 Feb 13;386(1):261-71. doi: 10.1016/j.jmb.2008.12.040. Epub 2008 Dec 24.
5
A macrophage receptor for apolipoprotein B48: cloning, expression, and atherosclerosis.载脂蛋白B48的巨噬细胞受体：克隆、表达与动脉粥样硬化
Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7488-93. doi: 10.1073/pnas.120184097.
6
Pathophysiology of triglyceride-rich lipoproteins in atherothrombosis: cellular aspects.富含甘油三酯的脂蛋白在动脉粥样硬化血栓形成中的病理生理学：细胞层面
Clin Cardiol. 1999 Jun;22(6 Suppl):II7-14. doi: 10.1002/clc.4960221403.
7
Characterization of five new mutants in the carboxyl-terminal domain of human apolipoprotein E: no cosegregation with severe hyperlipidemia.人载脂蛋白E羧基末端结构域五个新突变体的特征：与严重高脂血症无共分离现象。
Am J Hum Genet. 1993 May;52(5):937-46.
8
Metabolism by human endothelial cells of very low density lipoprotein subfractions isolated from type 1 (insulin-dependent) diabetic patients.1型（胰岛素依赖型）糖尿病患者极低密度脂蛋白亚组分在人内皮细胞中的代谢
Diabetologia. 1993 Mar;36(3):258-64. doi: 10.1007/BF00399960.
9
Accumulation of "small dense" low density lipoproteins (LDL) in a homozygous patients with familial defective apolipoprotein B-100 results from heterogenous interaction of LDL subfractions with the LDL receptor.在家族性载脂蛋白B - 100缺陷的纯合子患者中，“小而密”低密度脂蛋白（LDL）的积累是由于LDL亚组分与LDL受体的异质性相互作用所致。
J Clin Invest. 1993 Dec;92(6):2922-33. doi: 10.1172/JCI116915.
10
Relationship of an abnormal plasma lipoprotein to protection from atherosclerosis in the cholesterol-fed diabetic rabbit.胆固醇喂养的糖尿病兔中异常血浆脂蛋白与动脉粥样硬化防护的关系。
J Clin Invest. 1983 Nov;72(5):1553-62. doi: 10.1172/JCI111114.