Suppr超能文献

禽肉瘤和白血病病毒的第五种主要gag多肽p10的氨基末端氨基酸序列。

Amino-terminal amino acid sequence of p10, the fifth major gag polypeptide of avian sarcoma and leukemia viruses.

作者信息

Hunter E, Bennett J C, Bhown A, Pepinsky R B, Vogt V M

出版信息

J Virol. 1983 Feb;45(2):885-8. doi: 10.1128/JVI.45.2.885-888.1983.

Abstract

We have identified p10 as a fifth gag protein of avian sarcoma and leukemia viruses. Amino-terminal protein sequencing of this polypeptide purified from the Prague C strain of Rous sarcoma virus and from avian myeloblastosis virus implies that it is encoded within a stretch of 64 amino acid residues between p19 and p27 on the gag precursor polypeptide. For p10 from the Prague C strain of Rous sarcoma virus the first 30 residues were found to be identical with the predicted amino acid sequence from the Prague C strain of Rous sarcoma virus DNA sequence, whereas for p10 from avian myeloblastosis virus the protein sequence for the same region showed two amino acid substitutions. Amino acid composition data indicate that there are no gross composition changes beyond the region sequenced. The amino terminus of p10 is located two amino acid residues past the carboxy terminus of p19, whereas its carboxy terminus probably is located immediately adjacent to the first amino acid residue of p27.

摘要

我们已将p10鉴定为禽肉瘤和白血病病毒的第五种gag蛋白。对从劳氏肉瘤病毒布拉格C株和禽成髓细胞瘤病毒中纯化的该多肽进行氨基末端蛋白质测序表明,它由gag前体多肽上p19和p27之间的64个氨基酸残基编码。对于劳氏肉瘤病毒布拉格C株的p10,发现前30个残基与劳氏肉瘤病毒布拉格C株DNA序列预测的氨基酸序列相同,而对于禽成髓细胞瘤病毒的p10,同一区域的蛋白质序列有两个氨基酸取代。氨基酸组成数据表明,在测序区域之外没有明显的组成变化。p10的氨基末端位于p19羧基末端之后的两个氨基酸残基处,而其羧基末端可能紧邻p27的第一个氨基酸残基。

相似文献

引用本文的文献

本文引用的文献

9
Polyquarternary amines prevent peptide loss from sequenators.聚季铵盐可防止肽从测序仪中流失。
Anal Biochem. 1978 Feb;84(2):622-7?0=ENG. doi: 10.1016/0003-2697(78)90086-6.
10
Identification of retrovirus matrix proteins by lipid-protein cross-linking.
J Mol Biol. 1979 Jul 15;131(4):819-37. doi: 10.1016/0022-2836(79)90203-1.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验