Levitan E, Palti Y
J Theor Biol. 1983 Jan 7;100(1):107-11. doi: 10.1016/0022-5193(83)90095-4.
The characterizations of gating particles of ionic channels in nerve membranes by their equivalent valencies and their electric dipole moment changes are compared. The gating particle is represented as a system of electric charges in fixed positions in an external electric field and the potential energy of such a system is calculated in the approximation of a constant electric field. The proper expression of the Boltzmann distribution of the gating particles is presented. It is shown that the dipole moment of transition of the gating particle is the only proper thermodynamic (macroscopic) characteristics of the gating particles based on the available experimental information and does not depend on any microscopic assumption as the equivalent valency does.
比较了通过离子通道门控粒子的等效价及其电偶极矩变化对神经膜中离子通道门控粒子的表征。门控粒子被表示为处于外部电场中固定位置的电荷系统，并在恒定电场近似下计算该系统的势能。给出了门控粒子玻尔兹曼分布的恰当表达式。结果表明，基于现有实验信息，门控粒子跃迁的偶极矩是门控粒子唯一恰当的热力学（宏观）特征，并且不像等效价那样依赖于任何微观假设。
