大鼠嗅觉上皮匀浆诱导的双分子脂质膜中的单通道波动。

Single-channel fluctuations in bimolecular lipid membranes induced by rat olfactory epithelial homogenates.

作者信息

Vodyanoy V, Murphy R B

出版信息

Science. 1983 May 13;220(4598):717-9. doi: 10.1126/science.6301014.

Abstract

Chemosensitive single-channel fluctuations were observed to be induced in essentially solvent-free lipid bimolecular membranes by the addition of sonicated homogenates of rat olfactory epithelium. The chemosensitive channels were not observed when respiratory epithelium homogenates were used instead. Ionic selectivity is consistent with potassium ions as the charge carrier. These channels may be associated with the initial events of chemoreception in the rat olfactory epithelium.

摘要

通过添加大鼠嗅觉上皮的超声破碎匀浆，在基本无溶剂的脂质双分子膜中观察到化学敏感单通道波动。当使用呼吸道上皮匀浆替代时，则未观察到化学敏感通道。离子选择性与钾离子作为电荷载体一致。这些通道可能与大鼠嗅觉上皮中化学感受的初始事件有关。