动物和禽腺病毒基因组中反向末端重复序列的比较序列分析。

Comparative sequence analysis of the inverted terminal repetition in the genomes of animal and avian adenoviruses.

作者信息

Shinagawa M, Ishiyama T, Padmanabhan R, Fujinaga K, Kamada M, Sato G

出版信息

Virology. 1983 Mar;125(2):491-5. doi: 10.1016/0042-6822(83)90221-0.

Abstract

The nucleotide sequences at the inverted terminal repetitions from two animal adenoviruses, infectious canine hepatitis virus and equine adenovirus, and from one avian adenovirus, CELO, were analyzed. DNAs from infectious canine hepatitis virus and equine adenovirus contain a homologous region which is 23 nucleotides long from the terminus. The first 17 nucleotides of this region are identical to the ones in human adenovirus type 2 DNA. The striking homologous sequence of 14 nucleotides, conserved in the inverted terminal repetitions of several human adenovirus strains and in simian adenovirus type 7, is only partially conserved in the two animal and one avian adenoviruses reported here.

摘要

对两种动物腺病毒（传染性犬肝炎病毒和马腺病毒）以及一种禽腺病毒（CELO）的反向末端重复序列的核苷酸序列进行了分析。传染性犬肝炎病毒和马腺病毒的DNA含有一个同源区域，该区域从末端起长23个核苷酸。该区域的前17个核苷酸与2型人类腺病毒DNA中的核苷酸相同。在几种人类腺病毒株和7型猿猴腺病毒的反向末端重复序列中保守的14个核苷酸的显著同源序列，在本文报道的两种动物腺病毒和一种禽腺病毒中仅部分保守。