泪液中血管紧张素转换酶活性的测定。一种用于评估眼部结节病的非侵入性检测方法。

Determination of angiotensin-converting enzyme activity in tears. A noninvasive test for evaluation of ocular sarcoidosis.

作者信息

Sharma O P, Vita J B

出版信息

Arch Ophthalmol. 1983 Apr;101(4):559-61. doi: 10.1001/archopht.1983.01040010559004.

DOI:10.1001/archopht.1983.01040010559004

Abstract

Serum and tear samples were collected from 25 patients with sarcoidosis and from 55 healthy controls to determine angiotensin-converting enzyme activity. Seven of the ten patients with ocular sarcoidosis had greatly increased tear levels of the enzyme. The tear levels decreased when the disease subsided with prednisone therapy. The measurement of tear levels of the converting enzyme provides the best noninvasive test for diagnosing ocular sarcoidosis and monitoring the course of the disease.

摘要

收集了25例结节病患者和55名健康对照者的血清和泪液样本，以测定血管紧张素转换酶活性。10例眼部结节病患者中有7例泪液中该酶水平大幅升高。疾病在泼尼松治疗后缓解时，泪液水平下降。测量泪液中转换酶水平为诊断眼部结节病和监测疾病进程提供了最佳的非侵入性检测方法。