Immonen I, Friberg K, Sorsila R, Fyhrquist F
Acta Ophthalmol (Copenh). 1987 Feb;65(1):27-9. doi: 10.1111/j.1755-3768.1987.tb08486.x.
The concentration of angiotensin-converting enzyme (ACE) was studied in 39 patients with sarcoidosis, 6 of whom had active uveitis, 7 patients with non-sarcoid uveitis and 36 healthy controls. ACE concentration in tears was also compared with total protein concentration in tears in order to exclude the effect of varying dilution of tears at sampling. Mean tear ACE concentration and ACE/protein ratio were higher in patients with sarcoidosis than in controls. There were no significant differences in tear ACE concentration or ACE/protein ratio between sarcoidosis patients with uveitis and those with no eye involvement. Tear ACE concentration and ACE/protein ratio did not correlate significantly with serum ACE concentration. It is concluded that the mean concentration of tear ACE and ACE/protein ratio are elevated in sarcoidosis, but that this elevation is independent of any eye involvement.
对39例结节病患者、6例患有活动性葡萄膜炎的患者、7例非结节病性葡萄膜炎患者以及36名健康对照者的血管紧张素转换酶（ACE）浓度进行了研究。为排除采样时泪液稀释度不同的影响，还比较了泪液中ACE浓度与泪液总蛋白浓度。结节病患者的平均泪液ACE浓度和ACE/蛋白比值高于对照组。患有葡萄膜炎的结节病患者与无眼部受累的结节病患者之间，泪液ACE浓度或ACE/蛋白比值无显著差异。泪液ACE浓度和ACE/蛋白比值与血清ACE浓度无显著相关性。结论是，结节病患者的泪液ACE平均浓度和ACE/蛋白比值升高，但这种升高与任何眼部受累无关。
