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氯乙烯暴露后发生的肝细胞癌

[Hepatocellular carcinoma after exposure to vinyl chloride].

作者信息

Langbein G, Permanetter W, Dietz A

出版信息

Dtsch Med Wochenschr. 1983 May 13;108(19):741-5. doi: 10.1055/s-2008-1069633.

Abstract

Hepatocellular carcinoma was diagnosed already during life in a 54-year-old workman who had been exposed to high concentration of vinyl chloride due to his occupation for more than twenty years. In addition, typical early changes as seen in experimental vinyl chloride induced angiosarcoma were observed. In recent years permissible room air concentration of vinyl chloride at work have been lowered drastically. However, due to the long latency occurrence of malignant liver tumours may still be expected in persons exposed formerly. Within the search programme for such patients at risk ultrasonography and computed tomography as non-invasive methods with high accuracy are advisable.

摘要

一名54岁的工人在生前被诊断出患有肝细胞癌,他因职业原因接触高浓度氯乙烯超过20年。此外,还观察到了实验性氯乙烯诱导的血管肉瘤中典型的早期变化。近年来,工作场所空气中氯乙烯的允许浓度已大幅降低。然而,由于潜伏期长,以前接触过氯乙烯的人仍可能发生恶性肝肿瘤。在寻找此类高危患者的筛查计划中,超声检查和计算机断层扫描作为高精度的非侵入性方法是可取的。

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