Russell J A, Baker J W, Dady P J, Ford H T, Gazet J C, McKinna J A, Nash A G, Powles T J
Cancer. 1978 Feb;41(2):396-9. doi: 10.1002/1097-0142(197802)41:2<396::aid-cncr2820410203>3.0.co;2-t.
Fifty patients with metastatic breast cancer were treated with a combination of vincristine, Adriamycin and prednisolone (VAP) at four weekly intervals. Response rates of 78% for soft tissue disease, 66% for parenchymal lung disease, 67% for liver disease, and 64% for pleural effusions were seen. Only 26% of patients with bone metastases showed an objective response. These figures are as good as any previously reported for chemotherapy of breast cancer.
五十名转移性乳腺癌患者接受了长春新碱、阿霉素和泼尼松龙（VAP）联合治疗，每四周进行一次。软组织疾病的缓解率为78%，实质性肺部疾病为66%，肝脏疾病为67%，胸腔积液为64%。仅有26%的骨转移患者出现客观缓解。这些数据与先前报道的任何乳腺癌化疗效果一样好。
