Goldsweig H G, Brisson de Champlain M L, Davidman M
Cancer. 1978 Feb;41(2):568-77. doi: 10.1002/1097-0142(197802)41:2<568::aid-cncr2820410225>3.0.co;2-c.
Generalized aminoaciduria, uricosuria, glycosuria and phosphaturia were discovered in a patient with advanced Burkitt's lymphoma with renal infiltration. The literature is reviewed and three pathogenetic mechanisms are discussed. It is presumed that proximal tubular dysfunction in this case was related to the marked peritubular infiltrate causing cell mediated immunological injury or direct tubular destruction by tumor.
在一名患有晚期伯基特淋巴瘤并伴有肾浸润的患者中发现了全身性氨基酸尿、尿酸尿、糖尿和磷酸盐尿。本文回顾了相关文献并讨论了三种发病机制。据推测，该病例中的近端肾小管功能障碍与显著的肾小管周围浸润有关，这种浸润导致细胞介导的免疫损伤或肿瘤对肾小管的直接破坏。
