Hannon S M, Pickett A B, Frost J M
J Oral Maxillofac Surg. 1983 Jul;41(7):470-2. doi: 10.1016/0278-2391(83)90135-0.
A foreign-body granuloma may occur in the lip secondary to traumatic implantation of dirt and sand. Several recommendations for the clinician encountering such contaminated wounds follow. Debridement of the wound and copious flushing are of primary importance as a preventive measure. The patient should be informed of possible sequelae and advised to seek treatment if nodules occur in later years. The development of a granulomatous response necessitates initial surgical intervention to establish the histologic diagnosis; however, repeated surgical procedures are not indicated unless subsequent enlargements cannot be resolved by intralesional injection of steroids. Last, it must be emphasized that a histologic diagnosis of a granulomatous lesion obligates the oral and maxillofacial surgeon to request additional studies to rule out a systemic involvement.
异物肉芽肿可能继发于泥土和沙子的创伤性植入而发生在唇部。以下是给遇到此类污染伤口的临床医生的一些建议。伤口清创和大量冲洗作为预防措施至关重要。应告知患者可能的后遗症，并建议其如果在随后几年出现结节应寻求治疗。肉芽肿反应的发生需要最初进行手术干预以确立组织学诊断；然而，除非后续增大不能通过病灶内注射类固醇解决，否则不建议反复进行外科手术。最后，必须强调的是，肉芽肿性病变的组织学诊断要求口腔颌面外科医生要求进行额外检查以排除全身受累情况。
