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唇部填充后对羟基磷灰石钙的异物反应。

Foreign body reaction to calcium hydroxylapatite after lip augmentation.

作者信息

Sankar Vidya, McGuff H Stan

机构信息

Department of Dental Diagnostic Science, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, Mail Code 7919, San Antonio, Texas 78229, USA.

出版信息

J Am Dent Assoc. 2007 Aug;138(8):1093-6. doi: 10.14219/jada.archive.2007.0321.

DOI:10.14219/jada.archive.2007.0321
PMID:17670876
Abstract

BACKGROUND

Dentists need to be aware of soft-tissue lesions resulting from cosmetic facial/lip procedures that involve the use of injectable materials. Common side effects detected on clinical examination may include edema, bruising and noninflammatory lip nodules.

CASE DESCRIPTION

A 51-year-old woman visited a dental clinic with the chief complaint of a lump on the mucosal aspect of her lower lip. She reported having noted the lesion a few weeks before seeking care at the clinic. Several weeks later, the lesion persisted and new lesions were detected. The clinician excised the initial lesion only.

CLINICAL IMPLICATIONS

The lip nodules were associated with a cosmetic procedure and were inflammatory in nature. This is the first granulomatous response reported as a result of injections with calcium hydroxylapatite (Radiesse, BioForm Medical, San Mateo, Calif.). Poor patient recollection of his or her medical history may result in confusion with pathological processes such as infection, neoplasia or malignancy.

摘要

背景

牙医需要了解涉及使用可注射材料的面部/唇部美容手术所导致的软组织病变。临床检查中发现的常见副作用可能包括水肿、瘀伤和非炎性唇部结节。

病例描述

一名51岁女性因下唇黏膜面出现肿块为主诉前往牙科诊所就诊。她报告说在前往诊所就诊前几周就注意到了该病变。几周后,病变持续存在且发现了新的病变。临床医生仅切除了最初的病变。

临床意义

唇部结节与美容手术有关,本质上是炎性的。这是首次报告因注射羟基磷灰石钙(瑞蓝,BioForm Medical,加利福尼亚州圣马特奥)而出现的肉芽肿反应。患者对其病史回忆不佳可能会导致与感染、肿瘤形成或恶性肿瘤等病理过程相混淆。

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引用本文的文献

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Calcium Hydroxylapatite (CaHA) and Aesthetic Outcomes: A Systematic Review of Controlled Clinical Trials.羟基磷灰石钙(CaHA)与美学效果:对照临床试验的系统评价
J Clin Med. 2024 Mar 14;13(6):1686. doi: 10.3390/jcm13061686.
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Oral foreign body granuloma to soft tissue fillers. Report of two cases and review of the literature.口腔软组织填充剂异物肉芽肿。两例报告并文献复习。
J Clin Exp Dent. 2018 Feb 1;10(2):e177-e184. doi: 10.4317/jced.54191. eCollection 2018 Feb.
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Upper eyelid granuloma: a rare delayed-onset complication secondary to cosmetic filler injection on forehead.
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Int Med Case Rep J. 2016 Jun 23;9:155-7. doi: 10.2147/IMCRJ.S97356. eCollection 2016.
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J Clin Aesthet Dermatol. 2015 Jan;8(1):38-49.
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