Smith A W, Mattson D E, Skilling D E, Schmitz J A
Am J Vet Res. 1983 May;44(5):851-5.
A calicivirus was isolated from 3 dairy calves in a herd with persistent calf respiratory tract problems. This virus, named Tillamook calicivirus, was not neutralized by 18 different calicivirus-typing serums available. The agent caused only minimal lesions in 2 experimentally exposed calves, but did establish a persistent infection with virus shedding for 45 days, after which time the experiment was terminated. Experimentally exposed swine developed clinical vesicular lesions. The possible origins, disease potential, and relationships to the exotic animal disease agent, vesicular exanthema of swine are discussed for this first calicivirus isolate of bovine origin.
从一个存在持续性犊牛呼吸道问题的牛群中的3头犊牛体内分离出一种杯状病毒。这种病毒被命名为蒂拉穆克杯状病毒，现有18种不同的杯状病毒分型血清均不能将其中和。该病原体仅在2头经实验感染的犊牛身上引起了轻微病变，但确实建立了持续感染，病毒排出持续了45天，之后实验终止。经实验感染的猪出现了临床水疱性病变。本文针对这种首次分离出的牛源杯状病毒，讨论了其可能的起源、致病潜力以及与外来动物疾病病原体——猪水疱疹的关系。
