Berry E S, Skilling D E, Barlough J E, Vedros N A, Gage L J, Smith A W
College of Veterinary Medicine, Oregon State University, Corvallis 97331.
Am J Vet Res. 1990 Aug;51(8):1184-7.
A new serotype of calicivirus was isolated from California sea lions (Zalophus californianus) with severe vesicular disease. Neutralizing antibodies were found in 27 of 82 (32.9%) serum samples from California sea lions and in 15 of 146 (10.3%) serum samples from Steller sea lions (Eumetopias jubatus) tested. The seropositive animals were widely dispersed along the margins of the eastern Pacific basin, from the Bering Sea to the Santa Barbara Channel. Seropositive samples were found from as early as 1976 through the present time. This new calicivirus serotype, San Miguel sea lion virus type 13, was inoculated into weaned pigs, resulting in induction of severe vesicular disease, which spread to all pigs, including uninoculated pen contacts. Virus was continually shed by most of the pigs throughout the 2-week duration of the experiment.
从患有严重水疱病的加利福尼亚海狮（Zalophus californianus）中分离出一种新型杯状病毒。在检测的82份加利福尼亚海狮血清样本中有27份（32.9%）以及146份北海狗（Eumetopias jubatus）血清样本中有15份（10.3%）发现了中和抗体。血清反应阳性的动物广泛分布在东太平洋盆地边缘，从白令海到圣巴巴拉海峡。早在1976年至今都发现了血清反应阳性样本。这种新型杯状病毒血清型，即圣米格尔海狮病毒13型，接种到断奶仔猪体内，引发了严重水疱病，该病传播到所有猪，包括未接种的同圈接触猪。在整个为期2周的实验期间，大多数猪持续排毒。
