Galla J H, Bhathena D
Clin Nephrol. 1978 Jan;9(1):35-7.
Malacoplakia of the kidney is a rare histopathologic entity of unknown etiology. Patients may present with a renal mass or with urinary tract infection. The prognosis has been uniformly poor excepting in those patients with unilateral involvement treated by nephrectomy. A 31 year old woman presented with acute renal failure and pyelonephritis. Renal biopsy revealed an interstitial infiltrate of large histiocytic cells with intracytoplasmic PAS-positive granules and calcospherules, findings consistent with malacoplakia. Following antibiotic treatment and dialysis, the patient has had a gradual improvement in renal function.
肾软斑症是一种病因不明的罕见组织病理学实体。患者可能表现为肾肿块或尿路感染。除了接受肾切除术治疗的单侧受累患者外，预后一直很差。一名31岁女性出现急性肾衰竭和肾盂肾炎。肾活检显示有大量组织细胞的间质浸润，胞浆内有PAS阳性颗粒和钙化小体，这些发现符合软斑症。经过抗生素治疗和透析后，患者的肾功能逐渐改善。
