Członkowski A, Costa T, Przewłocki R, Pasí A, Herz A
Brain Res. 1983 May 16;267(2):392-6. doi: 10.1016/0006-8993(83)90897-1.
Opiate receptor binding sites were analyzed in various regions of human spinal cord and compared to results obtained in spinal cord and brain of certain animals. mu-, delta- and kappa binding sites were individually monitored by the overall labeling of opiate binding sites with [3H]diprenorphine followed by the sequential elimination of binding to particular sites by the use of selective ligands. kappa-Receptors were the predominant type (approximately 50%), followed by mu-receptors (approximately 40%), and, in rather small amounts, delta-receptors. A similar proportion of receptor types was found in the spinal cord of guinea pigs.
对人类脊髓的各个区域进行了阿片受体结合位点分析，并与在某些动物的脊髓和大脑中获得的结果进行了比较。通过用[3H]二丙诺啡对阿片结合位点进行整体标记，然后使用选择性配体依次消除与特定位点的结合，分别监测了μ、δ和κ结合位点。κ受体是主要类型（约50%），其次是μ受体（约40%），δ受体的含量较少。在豚鼠的脊髓中也发现了类似比例的受体类型。
