Amiel J L, Lasser P, Rougier P, Théodore C, Chahine G, Droz J P
Sem Hop. 1983 May 19;59(20):1513-7.
30 cases of digestive non-Hodgkin lymphomas are studied. Localization of the tumor was gastric in 14 cases, ileocoecal in 9 and in the small bowel in 7. Patients with gastric involvement are older (median 48 1/2 years) than those in the other groups (median 26 years). Management included maximal surgery followed by intensive chemotherapy with adriamycin, VM 26 and cyclophosphamide. This protocol gives excellent results: 85% lasting complete remissions with a median follow-up of 30 months and a maximal follow-up of 102 months. Failures occur only in the lymphoblastic cases which require a more intensive chemotherapy.
对30例消化系非霍奇金淋巴瘤进行了研究。肿瘤定位为胃的有14例,回盲部的有9例,小肠的有7例。胃受累患者(中位年龄48.5岁)比其他组患者(中位年龄26岁)年龄大。治疗包括最大限度的手术,随后用阿霉素、VM 26和环磷酰胺进行强化化疗。该方案取得了优异的效果:85%的患者持续完全缓解,中位随访时间为30个月,最长随访时间为102个月。仅在需要更强化化疗的淋巴母细胞性病例中出现失败情况。