Boiron M, Gisselbrecht C, Tricot G, Asselain B
Ann Gastroenterol Hepatol (Paris). 1984 Dec;20(6):331-7.
One third of all extranodal sites of non-Hodgkin's lymphomas are localized to the digestive tract. Forty-six cases with digestive tract localization were studied, of which 15 were localized forms. Histologically, 70 p. cent were diffuse lymphomas with poor prognosis. The present survival rate for localized forms following chemotherapy is 77 p. cent, which plateaux at two years, as compared to 34 p. cent for disseminated forms. Treatment of digestive tract localizations should be similar to that of nodal forms with the same histology. With the development of intensive chemotherapeutic regimens over the last few years, the cure rate is hoped to attain 65 p. cent in disseminated forms, and 87 p. cent in localized forms.
非霍奇金淋巴瘤所有结外部位中有三分之一局限于消化道。对46例消化道局限性病例进行了研究,其中15例为局限性类型。组织学上,70%为预后较差的弥漫性淋巴瘤。目前局限性类型化疗后的生存率为77%,两年后趋于平稳,而播散性类型为34%。消化道局限性病变的治疗应与相同组织学类型的淋巴结病变相似。随着过去几年强化化疗方案的发展,有望使播散性类型的治愈率达到65%,局限性类型达到87%。