Hilton A L, Warnock D W, Milne J D, Scott A J
Curr Med Res Opin. 1977;5(4):295-8. doi: 10.1185/03007997709110183.
An open trial was carried out in 50 women with clinical signs and mycological evidence of vaginal candidiasis to compare the effectiveness of treatment with 2% miconazole cream with that of nystatin pessaries. Both groups were given intravaginal treatment for 14 days and were followed up at monthly intervals for 3 months. Relief of symptoms and clinical signs was comparable in the two groups but the mycological cure rate at 1 month was higher with miconazole. At 2 and 3 months, however, there was no significant difference between the cure rate obtained with the two treatments in the patients still included in the study.
对50名有阴道念珠菌病临床症状和真菌学证据的女性进行了一项开放性试验，以比较2%咪康唑乳膏与制霉菌素阴道栓剂的治疗效果。两组均接受阴道内治疗14天，并每隔1个月随访3个月。两组症状和临床体征的缓解情况相当，但咪康唑治疗1个月时真菌学治愈率更高。然而，在第2和第3个月，仍纳入研究的患者中，两种治疗方法的治愈率无显著差异。
