受体聚集对扩散限制正向速率常数的影响。
The effect of receptor clustering on diffusion-limited forward rate constants.
作者信息
Goldstein B, Wiegel F W
出版信息
Biophys J. 1983 Jul;43(1):121-5. doi: 10.1016/S0006-3495(83)84330-6.
Abstract
The effect of receptor clustering on the diffusion-limited forward rate constant (k+) is studied theoretically by modeling cell surface receptors by hemispheres distributed on a plane. We give both exact results and bounds. The exact results are obtained using an electrostatic analogue and applying the method of the images. Accurate upper bounds on k+ are found from a variational principle.
摘要
通过将细胞表面受体模拟为分布在平面上的半球体，从理论上研究了受体聚集对扩散限制正向速率常数（k+）的影响。我们给出了精确结果和边界。精确结果是通过使用静电类比并应用镜像法获得的。通过变分原理找到了k+的精确上限。
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