Glaubitt D, Wagner W
Cancer Detect Prev. 1983;6(1-2):267-72.
In the serum of five patients with malignant germ cell tumor of the testis, prolactin as well as one or several of the gonadotropic, androgenic, estrogenic, and gestagenic hormones appeared to have the quality of tumor markers so that monitoring their serum level together with that of tissue polypeptide antigen, carcinoembryonic antigen, alpha-fetoprotein, and ferritin was useful. These compounds were determined by radioimmunoassay. Their serum concentration was often elevated although a constant pattern of findings or a relation to the severity of the disease was not observed. A corroboration of these results and an elucidation of their pathogenesis are necessary in a large number of patients.
在5例睾丸恶性生殖细胞瘤患者的血清中，催乳素以及一种或几种促性腺激素、雄激素、雌激素和孕激素似乎具有肿瘤标志物的性质，因此监测它们的血清水平以及组织多肽抗原、癌胚抗原、甲胎蛋白和铁蛋白的血清水平是有用的。这些化合物通过放射免疫测定法测定。尽管未观察到恒定的结果模式或与疾病严重程度的关系，但它们的血清浓度常常升高。需要在大量患者中对这些结果进行证实并阐明其发病机制。
