决定C57BL小鼠对埃可病毒感染天然抗性的机制。
Mechanisms determining innate resistance to ectromelia virus infection in C57BL mice.
作者信息
O'Neill H C, Blanden R V
出版信息
Infect Immun. 1983 Sep;41(3):1391-4. doi: 10.1128/iai.41.3.1391-1394.1983.
Abstract
The mechanism for innate resistance to ectromelia virus, which is controlled by a single gene in C57BL mice, was investigated. The cells or factors involved appear to be radioresistant and to impose an early barrier to viral penetration and spread via lymphatics or blood to the target organs, i.e., liver and spleen.
摘要
研究了C57BL小鼠中由单个基因控制的对痘苗病毒先天抗性的机制。所涉及的细胞或因子似乎具有抗辐射性，并对病毒通过淋巴管或血液渗透和传播到靶器官（即肝脏和脾脏）形成早期屏障。
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