Wright E S, Pike E, Couves C M
J Surg Oncol. 1983 Sep;24(1):23-9. doi: 10.1002/jso.2930240106.
Unusual lung tumors are not simply pathological curiosities. They demonstrate features of major significance in diagnosis, treatment, and prognosis. Six of these tumours are discussed: (1) Carcinosarcoma is rarely found in the lung. The histogenis of the lesion is unclear and the prognosis is poor. (2) Only three cases of pleomorphic adenoma have previously been described. Differentiation from other "mixed tumours" of the lung is essential. (3) A rare case of bronchial adenoma producing ectopic ACTH is described. Early recognition of these polypeptide hormone-secreting tumours is stressed. (4) Oat cell carcinoma with the myasthenic (Eaton-Lambert) syndrome shows the clinical features which should permit early tumour diagnosis. The hazards of muscle relaxants must be recognized. (5) Prostatic carcinoma with endobronchial metastases is is discussed. The importance of localization of the primary tumour is emphasized. (6) An example of double primary carcinoma is presented. The rarity of this finding may be related to the poor prognosis of patients with bronchogenesis carcinoma.
罕见肺部肿瘤并非仅仅是病理上的奇症。它们在诊断、治疗和预后方面具有重大意义。本文讨论了其中六种肿瘤:(1)癌肉瘤在肺部罕见。病变的组织发生不明,预后不良。(2)此前仅描述过三例多形性腺瘤。与肺部其他“混合性肿瘤”相鉴别至关重要。(3)描述了一例罕见的分泌异位促肾上腺皮质激素的支气管腺瘤。强调对这些分泌多肽激素肿瘤的早期识别。(4)伴有肌无力(伊顿 - 兰伯特)综合征的燕麦细胞癌具有可实现肿瘤早期诊断的临床特征。必须认识到肌肉松弛剂的风险。(5)讨论了伴有支气管内转移的前列腺癌。强调原发肿瘤定位的重要性。(6)给出了一例双原发性癌的例子。这一发现的罕见性可能与支气管源性癌患者的不良预后有关。