Wexler B C
Proc Soc Exp Biol Med. 1983 Sep;173(4):541-6. doi: 10.3181/00379727-173-41684.
Young Obese/SHR, genetically destined to become obese were made to run three times daily, averaging 2740 ft/day. Siblings of these young Obese/SHR which were allowed to remain sedentary, developed voracious appetites, massive obesity, hyperlipidemia, diabetes, hypertension, hyperadrenocorticism, muscle wasting, kidney stones, thin skin, and accelerated aging. The Obese/SHR that exercised did not become obese, their blood lipid, glucose, BUN, blood pressure, and hyperadrenocorticism were reduced, but their testes and ovaries became prematurely atrophic.
注定会肥胖的年轻肥胖/自发性高血压大鼠（Obese/SHR）每天进行三次跑步，平均每天跑2740英尺。这些年轻肥胖/自发性高血压大鼠的未运动的同窝出生仔畜出现了食欲旺盛、重度肥胖、高脂血症、糖尿病、高血压、肾上腺皮质功能亢进、肌肉萎缩、肾结石、皮肤变薄和加速衰老。进行运动的肥胖/自发性高血压大鼠没有变得肥胖，它们的血脂、血糖、血尿素氮、血压和肾上腺皮质功能亢进情况有所减轻，但它们的睾丸和卵巢过早萎缩。
