刺激中枢α-肾上腺素能受体的药理学证据。
Pharmacological evidence of the stimulation of central alpha-adrenergic receptors.
作者信息
Simon P, Chermat R, Puech A J
出版信息
Prog Neuropsychopharmacol Biol Psychiatry. 1983;7(2-3):183-6. doi: 10.1016/0278-5846(83)90105-7.
PMID:6310690
Abstract
We studied the interactions between CRL 40028 (benzhydryl sulfinyl) acetohydroxamic acid) and the alpha 1 blocker prazosin, in mouse. CRL 40028 antagonizes prazosin-induced hypothermia and hypomotility; prazosin antagonizes the anticonvulsant effect of CRL 40028 in the quaking mouse.
摘要
我们在小鼠体内研究了CRL 40028（二苯甲基亚磺酰基）乙酰氧肟酸与α1阻滞剂哌唑嗪之间的相互作用。CRL 40028可拮抗哌唑嗪诱导的体温过低和运动减少；哌唑嗪可拮抗CRL 40028对震颤小鼠的抗惊厥作用。
Zotero 插件