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[洛林地区废水中肠道病毒的传播。1976 - 1981年一项调查的评估]

[Enterovirus circulation in the waste waters of the Lorraine region. Evaluation of a survey 1976-1981].

作者信息

Agbalika F, Hartemann P, Brigaud M, Foliguet J M

出版信息

Rev Epidemiol Sante Publique. 1983;31(2):209-21.

PMID:6310709
Abstract

A survey of the presence of viruses in wastewater has been conducted during 6 years in 19 treatment plants of the lorraine area. The results presented in this paper show the presence of numerous viral species in the 1938 samples analyzed from 1976 to 1981 and large variations of the annual positivity rate linked to the circulation of enteric viruses in the population. By direct inoculation to cell cultures the search of virus is positive in only 15% of the samples. On the other hand a previous concentration step allows to obtain an increase of positive samples. Taking into account the important aptitudes of polio and non poliovirus to survive in water, the survey of wastewater could be a good indicator of their presence in the population. The isolation of non vaccinal polioviruses confirm the need of the continuation of the vaccination program, but perhaps also a reevaluation of the rule of the living oral vaccine because of the presence of so called "intermediary strains".

摘要

在6年时间里,对洛林地区的19家污水处理厂的废水病毒存在情况进行了调查。本文给出的结果显示,在1976年至1981年分析的1938个样本中存在大量病毒种类,且年度阳性率与肠道病毒在人群中的传播情况有很大差异。通过直接接种到细胞培养物中,仅15%的样本病毒检测呈阳性。另一方面,预先进行浓缩步骤可使阳性样本数量增加。考虑到脊髓灰质炎病毒和非脊髓灰质炎病毒在水中具有很强的存活能力,废水调查可能是它们在人群中存在情况的良好指标。非疫苗株脊髓灰质炎病毒的分离证实了继续实施疫苗接种计划的必要性,但或许也需要重新评估口服活疫苗的使用规则,因为存在所谓的“中间毒株”。

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