Gilman S C, Ackerman M J, Hallenbeck J M, Faden A
Undersea Biomed Res. 1983 Jun;10(2):89-93.
Naloxone in doses up to 2 mg/kg and beta-endorphin in doses up to 1 mg/kg had no suppressive effect on pressure-induced tremor or cortical EEG activity in the guinea pig. The lack of effect of either naloxone or beta-endorphin on the HPNS provides evidence that opiate receptor mechanisms are not significantly involved in this syndrome.
剂量高达2毫克/千克的纳洛酮和剂量高达1毫克/千克的β-内啡肽对豚鼠的压力诱导性震颤或皮层脑电图活动没有抑制作用。纳洛酮或β-内啡肽对高位脊髓神经综合征均无作用，这表明阿片受体机制在该综合征中没有显著参与。
