Mizukoshi K, Kobayashi H, Ohashi N, Watanabe Y
Acta Otolaryngol Suppl. 1983;393:58-64. doi: 10.3109/00016488309129578.
In order to investigate interaction of the vestibular and optokinetic system, a visual vestibulo-ocular reflex (V-VOR) gain in forty-five normal subjects was measured by manual and computer analysis. The test subjects sat in a newly devised, pendular rotating chair in an optokinetic drum. With this device pendular harmonic sinusoidal rotation and optokinetic stimuli could be given simultaneously. The test subjects were rotated sinusoidally at amplitudes of 120 degrees and 240 degrees and at frequencies of 0.05 Hz and 0.1 Hz (maximum velocities 18.8 degrees/s, 37.7 degrees/s, 75.4 degrees/s), and with eyes closed and open. Within these pendular stimuli, there was no response decline phenomenon nor influence of amplitude on frequency. The pure VOR gain measured in dark room with eyes open was about 0.6 and did not vary with the eyes closed as long as mental alertness was maintained. The V-VOR gain in a stationary optokinetic drum with eyes open was about 1.1. From our observations, the 0.1 Hz sinusoidal rotation with an amplitude of 240 degrees (maximum velocity, 75.4 degrees/s) is an appropriate stimulation for the V-VOR and VOR test battery in clinical practice.
为研究前庭系统与视动系统的相互作用，采用手动和计算机分析方法测量了45名正常受试者的视-前庭眼反射（V-VOR）增益。受试者坐在视动鼓内新设计的摆式旋转椅上。利用该装置可同时给予摆式谐波正弦旋转和视动刺激。受试者以120度和240度的幅度、0.05赫兹和0.1赫兹的频率（最大速度分别为18.8度/秒、37.7度/秒、75.4度/秒）进行正弦旋转，旋转时眼睛闭合和睁开。在这些摆式刺激下，未出现反应下降现象，且幅度对频率无影响。在暗室中睁眼测量的纯VOR增益约为0.6，只要保持精神警觉，闭眼时该增益不变。在静止视动鼓中睁眼时的V-VOR增益约为1.1。根据我们的观察，240度幅度（最大速度75.4度/秒）的0.1赫兹正弦旋转是临床实践中对V-VOR和VOR测试组的合适刺激。
