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糙米和大豆膳食纤维对糖尿病大鼠糖脂代谢控制的影响。

Effect of brown rice and soybean dietary fiber on the control of glucose and lipid metabolism in diabetic rats.

作者信息

Madar Z

出版信息

Am J Clin Nutr. 1983 Sep;38(3):388-93. doi: 10.1093/ajcn/38.3.388.

Abstract

We have studied the effect of brown rice and soybean dietary fiber on the oral glucose tolerance test, plasma-insulin, -glucagon, -triglycerides, and cholesterol levels in control and streptozotocin-induced diabetic rats. Plasma glucose level after glucose loading in diabetic rats fed soybean fiber was considerably lower (60 and 120 min) than the corresponding group not receiving the fiber. Soybean fiber given to control rats decreased the plasma glucose at 60 min after the oral glucose test. Rice fiber decreased the plasma glucose of diabetic rats only at 60 min and the control rats fed with or without fiber elicited a comparable glycemic response. While soybean fiber significantly lowered the glucagon and triglyceride levels in both control and diabetic rats, rice fiber had no effect on these blood parameters. In conclusion, this study demonstrated the potential benefit of soybean dietary fiber over rice fiber in diabetes treatment with additional advantages resulting from its ease in usage either in a mixture of water or milk products and cooking. As well, being devoid of a disagreeable taste so characteristic of other fibers, patient acceptance is more forthcoming.

摘要

我们研究了糙米和大豆膳食纤维对正常及链脲佐菌素诱导的糖尿病大鼠口服葡萄糖耐量试验、血浆胰岛素、胰高血糖素、甘油三酯和胆固醇水平的影响。喂食大豆纤维的糖尿病大鼠在葡萄糖负荷后的血浆葡萄糖水平(60分钟和120分钟时)显著低于未接受纤维的相应组。给予正常大鼠大豆纤维可使口服葡萄糖试验后60分钟时的血浆葡萄糖降低。米纤维仅在60分钟时降低糖尿病大鼠的血浆葡萄糖,且无论是否喂食纤维,正常大鼠的血糖反应相当。虽然大豆纤维显著降低了正常和糖尿病大鼠的胰高血糖素和甘油三酯水平,但米纤维对这些血液参数没有影响。总之,本研究表明,在糖尿病治疗中,大豆膳食纤维比米纤维具有潜在益处,因其易于与水或奶制品混合使用及烹饪,还有其他优势。此外,大豆纤维没有其他纤维特有的难闻味道,患者更容易接受。

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