去甲肾上腺素对齿状回群体锋电位的长时程增强作用。
Long-lasting potentiation of the dentate gyrus population spike by norepinephrine.
作者信息
Neuman R S, Harley C W
出版信息
Brain Res. 1983 Aug 22;273(1):162-5. doi: 10.1016/0006-8993(83)91106-x.
PMID:6311345
Abstract
The effects of iontophoretically applied norepinephrine (NE) on the dentate gyrus field potential evoked by perforant path stimulation were examined. NE potentiated the population spike by 20-400%, whereas the population EPSP was rarely increased. At 39% of the potentiated sites NE application resulted in long-lasting potentiation (LLP) suggesting a role for NE in long-term hippocampal plasticity.
摘要
研究了离子电渗法应用去甲肾上腺素（NE）对穿通通路刺激诱发的齿状回场电位的影响。NE使群体峰电位增强20% - 400%，而群体兴奋性突触后电位很少增加。在39%的增强位点，应用NE导致了长时程增强（LLP），提示NE在海马体长期可塑性中发挥作用。
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