α2HS糖蛋白受体与爱泼斯坦-巴尔病毒核抗原（EBNA）相同的证据。

Evidence that the alpha 2HS glycoprotein receptor and the Epstein-Barr virus nuclear antigen (EBNA) are identical.

作者信息

Lewis J G, André C M

出版信息

FEBS Lett. 1983 Sep 19;161(2):306-10. doi: 10.1016/0014-5793(83)81030-8.

Abstract

Evidence is presented which suggests that the alpha 2HS glycoprotein (alpha 2HS) receptor on lymphocytes transformed by Epstein-Barr virus (EBV) and the EBV-determined nuclear antigen (EBNA) are immunologically related, and may be identical. Western blotting, using both anti-EBNA and anti-alpha 2HS receptor serum identified a similar Mr 48 000 component in labelled detergent-solubilized transformed cell supernatants. The Mr 48 000 component recognized by anti-EBNA serum had a pI between 7-8, similar to that reported for the alpha 2HS receptor.

摘要

现有证据表明，由爱泼斯坦 - 巴尔病毒（EBV）转化的淋巴细胞上的α2HS糖蛋白（α2HS）受体与EBV确定的核抗原（EBNA）在免疫学上相关，并且可能是相同的。使用抗EBNA和抗α2HS受体血清进行的蛋白质免疫印迹法在标记的经去污剂溶解的转化细胞上清液中鉴定出一种类似的分子量为48000的成分。抗EBNA血清识别的分子量为48000的成分的等电点在7至8之间，与报道的α2HS受体的等电点相似。