具有延长肽链的新型促吞噬肽类似物的合成及生物学研究

Synthesis and biological investigations of new tuftsin analogs with elongated peptide chain.

作者信息

Konopinska D, Luczak M, Gumułka S

出版信息

Int J Pept Protein Res. 1983 Aug;22(2):223-30. doi: 10.1111/j.1399-3011.1983.tb02089.x.

DOI:10.1111/j.1399-3011.1983.tb02089.x

Abstract

In this paper the synthesis of the following elongated tuftsin analogs: Thr-Lys-Pro-Lys-Thr-Lys-Pro-Lys (I), Thr-Lys-Pro-Lys-Thr-Lys-Pro-Arg (II) and Ala-Lys-Thr-Lys-Pro-Arg-Glu-Gln (III) by the classical method is described. The compound II markedly inhibited the growth of murine sarcoma viruses (MSV).

摘要