Ascorbic acid could be hazardous to your experiments: a commentary on dopamine receptor binding studies with speculation on a role for ascorbic acid in neuronal function.

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作者信息

Hadjiconstantinou M, Neff N H

出版信息

Neuropharmacology. 1983 Aug;22(8):939-43. doi: 10.1016/0028-3908(83)90209-5.

DOI:10.1016/0028-3908(83)90209-5

PMID:6312359

Abstract

摘要

相似文献

Ascorbic acid could be hazardous to your experiments: a commentary on dopamine receptor binding studies with speculation on a role for ascorbic acid in neuronal function.

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Differential effects of ascorbate and EDTA on high-affinity binding of 3H-apomorphine and 3H-ADTN to calf caudate membranes.抗坏血酸盐和乙二胺四乙酸对3H-阿扑吗啡和3H-ADTN与小牛尾状核膜高亲和力结合的差异效应。

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Ascorbic acid enables reversible dopamine receptor 3H-agonist binding.抗坏血酸可使多巴胺受体3H-激动剂结合可逆。

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The role of dopamine receptors in the neurobehavioral syndrome provoked by activation of L-type calcium channels in rodents.多巴胺受体在啮齿动物中由L型钙通道激活引发的神经行为综合征中的作用。

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Ascorbic Acid to Manage Psychiatric Disorders.抗坏血酸治疗精神障碍。

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Ascorbic acid treatment elevates follicle stimulating hormone and testosterone plasma levels and enhances sperm quality in albino Wistar rats.

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Ascorbic Acid inhibits development of tolerance and dependence to opiates in mice: possible glutamatergic or dopaminergic modulation.

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Supplementation of vitamin C with atypical antipsychotics reduces oxidative stress and improves the outcome of schizophrenia.使用非典型抗精神病药物时补充维生素C可减轻氧化应激并改善精神分裂症的治疗效果。

Psychopharmacology (Berl). 2005 Nov;182(4):494-8. doi: 10.1007/s00213-005-0117-1. Epub 2005 Oct 19.

Ascorbic acid stimulates gonadotropin release by autocrine action by means of NO.抗坏血酸通过一氧化氮的自分泌作用刺激促性腺激素释放。

Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11783-8. doi: 10.1073/pnas.191369398. Epub 2001 Sep 18.

Ascorbic acid acts as an inhibitory transmitter in the hypothalamus to inhibit stimulated luteinizing hormone-releasing hormone release by scavenging nitric oxide.抗坏血酸在下丘脑中作为一种抑制性递质，通过清除一氧化氮来抑制刺激后的促黄体生成素释放激素的释放。

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Repeated treatment with ascorbate or haloperidol, but not clozapine, elevates extracellular ascorbate in the neostriatum of freely moving rats.用抗坏血酸盐或氟哌啶醇而非氯氮平反复处理自由活动大鼠的新纹状体，可提高细胞外抗坏血酸盐水平。

Psychopharmacology (Berl). 1994 Sep;116(1):103-9. doi: 10.1007/BF02244879.

Comparison of release of endogenous dopamine and gamma-aminobutyric acid from rat caudate synaptosomes.大鼠尾状核突触体释放内源性多巴胺和γ-氨基丁酸的比较。

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Ascorbate antagonizes the behavioral effects of amphetamine by a central mechanism.

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Functional consequences following methamphetamine-induced neuronal damage.

Psychopharmacology (Berl). 1989;97(4):432-5. doi: 10.1007/BF00439543.

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