蜘蛛大腹园蛛毒液提取物对谷氨酸受体的特异性拮抗作用。
Specific antagonism of the glutamate receptor by an extract from the venom of the spider Araneus ventricosus.
作者信息
Kawai N, Miwa A, Abe T
出版信息
Toxicon. 1983;21(3):438-40. doi: 10.1016/0041-0101(83)90101-0.
PMID:6312632
Abstract
A venom sac extract selectively and irreversibly suppressed excitatory postsynaptic potentials in the lobster neuromuscular junction without affecting inhibitory postsynaptic potentials. Glutamate-induced depolarization of the postsynaptic membrane was blocked by the venom extract, whereas membrane depolarization by aspartate was unaffected.
摘要
一种毒囊提取物能选择性且不可逆地抑制龙虾神经肌肉接头处的兴奋性突触后电位，而不影响抑制性突触后电位。毒囊提取物可阻断谷氨酸诱导的突触后膜去极化，而天冬氨酸引起的膜去极化则不受影响。
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