Demisch K, Demisch L, Bochnik H J, Schulz F
Am J Psychiatry. 1983 Nov;140(11):1511-2. doi: 10.1176/ajp.140.11.1511.
Fourteen depressed patients were given the dexamethasone and ACTH suppression tests. The results of 71% agreed, suggesting that in a subgroup of depressed patients dexamethasone resistance reflects a central rather than peripheral dysfunction of the hypothalamic-pituitary-adrenal axis.
对14名抑郁症患者进行了地塞米松和促肾上腺皮质激素抑制试验。71%的结果一致,表明在一部分抑郁症患者中,地塞米松抵抗反映了下丘脑-垂体-肾上腺轴的中枢而非外周功能障碍。