小鼠乳腺肿瘤病毒胞质内A颗粒反应性抗体在哺乳动物中的广泛存在。
Widespread occurrence in mammals of antibodies reactive to intracytoplasmic A particles of the mouse mammary tumor virus.
作者信息
Zotter S
出版信息
Arch Geschwulstforsch. 1983;53(4):315-9.
PMID:6312921
Abstract
Serum antibodies reactive to clusters of intracytoplasmic A particles in mouse mammary tumors and leukemia cells by means of an indirect immunofluorescence assay were detected in 11 mammalian species (ranging in frequency from 5.1 to 29.3%). These antibodies could not be found in sera from chicken, ducks and geese. Their presence in so many mammalian species, not only in mammary tumor virus-infected mice, sheds new light on similar antibodies in man detected 10 years ago.
摘要
通过间接免疫荧光测定法，在11种哺乳动物中检测到了对小鼠乳腺肿瘤和白血病细胞中胞质内A颗粒簇具有反应性的血清抗体（频率范围为5.1%至29.3%）。在鸡、鸭和鹅的血清中未发现这些抗体。它们在如此多的哺乳动物物种中存在，不仅在感染乳腺肿瘤病毒的小鼠中，为10年前在人类中检测到的类似抗体提供了新的线索。
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