行为与结合：对α1-肾上腺素能刺激引起的听觉惊吓反应脱敏与α1-肾上腺素能受体结合位点的减少有关。
Behavior and binding: desensitization to alpha 1-adrenergic stimulation of acoustic startle is associated with a decrease in alpha 1-adrenoceptor binding sites.
作者信息
Astrachan D I, Gallager D W, Davis M
出版信息
Brain Res. 1983 Oct 3;276(1):183-7. doi: 10.1016/0006-8993(83)90562-0.
PMID:6313129
Abstract
Desensitization of the excitatory effects of alpha 1-adrenergic agonists on acoustic startle occurred 6 h after intrathecal administration of the alpha 1-adrenergic agonist, phenylephrine. This desensitization was associated with a decrease in alpha 1-adrenoceptor sites in the lumbar spinal cord.
摘要
鞘内注射α1肾上腺素能激动剂去氧肾上腺素6小时后，α1肾上腺素能激动剂对听觉惊吓的兴奋作用出现脱敏。这种脱敏与腰段脊髓中α1肾上腺素能受体位点的减少有关。
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