Morris M J, Woodcock E A
Clin Exp Pharmacol Physiol. 1983 May-Jun;10(3):341-4. doi: 10.1111/j.1440-1681.1983.tb00209.x.
The effect of bilateral sino-aortic denervation on cardiac and renal cortical alpha- and beta-adrenoceptor concentrations was studied in rats by radioligand binding experiments using [3H]-prazosin (alpha 1), [3H]-yohimbine (alpha 2) and [125I]-iodocyanopindolol (beta). Cardiac alpha 1- and beta-adrenoceptor concentrations were not altered by sino-aortic denervation. There was a significant increase in beta-adrenoceptor concentration in the renal cortex of sino-aortic denervated rats compared to sham-operated controls.
通过使用[3H]-哌唑嗪（α1）、[3H]-育亨宾（α2）和[125I]-碘氰吲哚洛尔（β）的放射性配体结合实验，研究了双侧窦主动脉去神经支配对大鼠心脏和肾皮质α和β肾上腺素能受体浓度的影响。窦主动脉去神经支配未改变心脏α1和β肾上腺素能受体浓度。与假手术对照组相比，窦主动脉去神经支配大鼠肾皮质中的β肾上腺素能受体浓度显著增加。
