Comhaire F, Simons M, Kunnen M, Vermeulen L
J Urol. 1983 Nov;130(5):923-6. doi: 10.1016/s0022-5347(17)51578-5.
Rapid sequence scintigraphy was used to study testicular arterial perfusion and venous stasis in 53 patients with varicocele-associated infertility, 17 with idiopathic testicular failure and 9 treated for varicocele. Arterial blood supply to the diseased testicle was decreased in 63 per cent of the patients with subclinical or low grade varicocele compared to 18 per cent with idiopathic testicular failure. In the majority of cases the disturbance of perfusion disappeared immediately after interruption of retrograde blood flow in the internal spermatic vein by transcatheter embolization, whereas persistently impaired perfusion was found in a few cases with no improvement of semen quality after treatment. Venous stasis was found in only 18 per cent of the patients with low grade varicocele compared to 88 per cent with large varicoceles. It is suggested that impaired arterial blood supply rather than venous stasis is the pathogenic factor in epididymo-testicular dysfunction associated with low grade varicocele.
采用快速序列闪烁扫描法研究了53例精索静脉曲张相关性不育患者、17例特发性睾丸功能衰竭患者以及9例接受精索静脉曲张治疗患者的睾丸动脉灌注和静脉淤滞情况。与18%的特发性睾丸功能衰竭患者相比,63%的亚临床型或轻度精索静脉曲张患者患侧睾丸的动脉血供减少。在大多数病例中,通过经导管栓塞术阻断精索内静脉的逆流后,灌注障碍立即消失,而在少数治疗后精液质量未改善的病例中发现灌注持续受损。轻度精索静脉曲张患者中仅18%存在静脉淤滞,而重度精索静脉曲张患者中这一比例为88%。提示动脉血供受损而非静脉淤滞是与轻度精索静脉曲张相关的附睾-睾丸功能障碍的致病因素。