Joseph S A, Pilcher W H, Bennett-Clarke C
Neurosci Lett. 1983 Aug 8;38(3):221-5. doi: 10.1016/0304-3940(83)90372-5.
Immunocytochemical localization of ACTH-opiocortin perikarya was demonstrated in the medulla of colchicine-treated rat. Neuronal cell bodies and fibers containing ACTH-immunoreactivity were abundant in the caudal region of the nucleus tractus solitarius, specifically within pars commisuralis. Location of these opiocortin neurons within the nucleus tractus solitarius provides additional evidence for a role of these peptides in cardiovascular functions.
在秋水仙碱处理的大鼠延髓中证实了促肾上腺皮质激素-阿片皮质素核周体的免疫细胞化学定位。在孤束核的尾侧区域,特别是在连合部,含有促肾上腺皮质激素免疫反应性的神经元细胞体和纤维丰富。这些阿片皮质素神经元在孤束核内的定位为这些肽在心血管功能中的作用提供了额外的证据。