神经垂体中间部中β-内啡肽样免疫反应性的昼夜变化。
Circadian variation of beta-endorphin-like immunoreactivity in neurointermediate pituitary.
作者信息
Gibson M J, Colurso G J, Applebaum L, Krieger D T
出版信息
Peptides. 1983 May-Jun;4(3):305-9. doi: 10.1016/0196-9781(83)90138-9.
PMID:6314293
Abstract
Immunoreactive beta-endorphin-like activity (-IR) and ACTH-IR were determined in rat pituitary lobes and plasma at 4-hr intervals over a 24-hr period. In addition, we measured beta-endorphin-IR in discrete hypothalamic nuclei, and plasma corticosterone levels at the same time points. Significant and replicable circadian variation was detected only in concentrations of beta-endorphin-IR in neurointermediate pituitary and in plasma corticosterone concentrations.
摘要
在24小时内，每隔4小时测定大鼠垂体叶和血浆中的免疫反应性β-内啡肽样活性（-IR）和促肾上腺皮质激素-IR。此外，我们在同一时间点测量了离散下丘脑核中的β-内啡肽-IR以及血浆皮质酮水平。仅在神经垂体中间叶的β-内啡肽-IR浓度和血浆皮质酮浓度中检测到显著且可重复的昼夜节律变化。
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