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酮康唑在猫和狗皮肤真菌病治疗中的应用

Ketoconazole in the treatment of dermatomycosis in cats and dogs.

作者信息

De Keyser H, Van den Brande M

出版信息

Vet Q. 1983 Jul;5(3):142-4. doi: 10.1080/01652176.1983.9693888.

DOI:10.1080/01652176.1983.9693888
PMID:6314635
Abstract

Ketoconazole (Nizoral, Janssen Pharmaceutica) a new systemic antimycotic was tested in dermatomycosis in cats and dogs. The daily dose (10 mg/kg body weight) was administered for 10 or 20 days without any other measures being taken. After the 20-day treatments new hair growth was observed in 96.7 per cent of the cats and 89.9 per cent of the dogs. Clinical cure was complete in 96.8 per cent of the cats and 90.5 per cent of the dogs. Particularly the good tolerance in the cat was appreciated. There were practically no side-effects in dogs (except vomiting in two pups) or in cats.

摘要

酮康唑(里素劳,杨森制药公司)是一种新型全身性抗真菌药,在猫和狗的皮肤真菌病治疗中进行了试验。每日剂量(10毫克/千克体重)给药10或20天,未采取任何其他措施。20天治疗后,观察到96.7%的猫和89.9%的狗有新毛发生长。96.8%的猫和90.5%的狗实现了临床治愈。尤其值得一提的是猫对该药的耐受性良好。狗(除两只幼犬呕吐外)和猫几乎没有副作用。

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