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[苏联新型与市售乙型脑炎预防疫苗的反应原性和免疫原性对比研究]

[Comparative study of the reactogenicity and immunogenicity of new Soviet and commercial vaccines for preventing Japanese encephalitis].

作者信息

Sumarovkov A A, Grachev V P, Kharazian E G, Shkol'nik R Ia, Vorob'eva M S

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1983 Sep(9):74-9.

PMID:6314716
Abstract

In this article the results of testing Soviet vaccines for the prophylaxis of Japanese encephalitis, cell-culture inactivated adsorbed liquid vaccine and brain-tissue purified dried vaccine, are generalized and the comparison of their reactogenicity and immunogenicity characteristics with those of a similar commercial preparation manufactured by Toshiba Kagaku Kogyo Co., Ltd. (Japan) is made. Cell-culture inactivated liquid vaccine has proved to be the optimal preparation: it produces the most prolonged and intensive immunity and, when introduced by two methods, shows low reactogenicity.

摘要

本文总结了苏联预防日本脑炎疫苗——细胞培养灭活吸附液体疫苗和脑组织纯化干燥疫苗的测试结果,并将它们与日本东芝化学工业株式会社生产的类似商业制剂的反应原性和免疫原性特征进行了比较。细胞培养灭活液体疫苗已被证明是最佳制剂:它能产生最持久、强烈的免疫力,并且通过两种接种方法接种时,反应原性较低。

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