β-肾上腺素能兴奋剂对纤毛运动的增强作用。

Enhancement of ciliary action by a beta-adrenergic stimulant.

作者信息

Ohashi Y, Nakai Y, Zushi K, Muraoka M, Minowa Y, Harada H, Masutani H

出版信息

Acta Otolaryngol Suppl. 1983;397:49-59. doi: 10.3109/00016488309105585.

Abstract

It is known that beta-adrenergic stimulants enhance mucociliary transport in the respiratory tract. The present study clearly indicated that such an enhancement resulted from not only the alteration in secretory function but also the direct stimulation of ciliated cells. However, the enhancement of ciliary beating depended on the morphological changes in ciliated cells. On the other hand, the effect of terbutaline aerosol, a beta-adrenergic stimulant, on patients with chronic sinusitis was evaluated by paranasal sinus radiography. Consequently, marked improvements in shadows were achieved after 4 weeks in 40% of the cases examined.

摘要

已知β-肾上腺素能兴奋剂可增强呼吸道的黏液纤毛运输。本研究清楚地表明，这种增强不仅源于分泌功能的改变，还源于对纤毛细胞的直接刺激。然而，纤毛摆动的增强取决于纤毛细胞的形态变化。另一方面，通过鼻窦X线摄影评估了β-肾上腺素能兴奋剂特布他林气雾剂对慢性鼻窦炎患者的影响。结果，在40%的受检病例中，4周后阴影有明显改善。