人及仓鼠实验性胰腺癌中的视黄酸结合蛋白
Retinoic acid binding protein in human and experimental pancreatic carcinomas in hamsters.
作者信息
Brandes M, Gesell M S, Ueda H, Millan J C, Quinlan R M, Ernst C, Sindelar W F, Kurman C C, Harris S, Brandes D
出版信息
Ann Clin Lab Sci. 1983 Sep-Oct;13(5):400-6.
PMID:6314868
Abstract
Cytoplasmic retinoic acid binding protein (cRABP) is present in human fetal pancreas and becomes nondetectable in the normal adult pancreas. The binding protein for retinoic acid becomes apparent again in pancreatic cancer. Similar fluctuations in the content of cRABP occur in the hamster. The binding protein is undetectable in the normal adult hamster pancreas, while it was detected in several transplantable adenocarcinomas in the Syrian golden hamster.
摘要
细胞质视黄酸结合蛋白（cRABP）存在于人类胎儿胰腺中，而在正常成年胰腺中无法检测到。视黄酸结合蛋白在胰腺癌中再次出现。仓鼠体内cRABP的含量也有类似的波动。正常成年仓鼠胰腺中检测不到该结合蛋白，而在叙利亚金仓鼠的几种可移植腺癌中检测到了它。
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