川楝素的抗肉毒杆菌作用及其对微小终板电位的易化作用。
Anti-botulismic effect of toosendanin and its facilitatory action on miniature end-plate potentials.
作者信息
Shih Y L, Hsu K
出版信息
Jpn J Physiol. 1983;33(4):677-80. doi: 10.2170/jjphysiol.33.677.
PMID:6315997
Abstract
The time for blocking neuromuscular transmission by botulinum toxin is lengthened in phrenic nerve-diaphragm preparation of rats sacrificed at various times after subcutaneous injection of toosendanin (7 mg/kg). This effect of toosendanin manifests itself 15 min after injection and lasts for 3 days. During this period the frequency of miniature end-plate potentials is increased.
摘要
在皮下注射川楝素（7毫克/千克）后不同时间处死的大鼠膈神经-膈肌标本中，肉毒杆菌毒素阻断神经肌肉传递的时间延长。川楝素的这种作用在注射后15分钟出现，并持续3天。在此期间，微小终板电位的频率增加。
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