Reavy B, Pullin J S, Moore N F
Microbios. 1983;38(152):91-8.
Picornavirus infection of Drosophila melanogaster cells inhibited the appearance of heat-shock induced proteins. Examination of intracellular mRNAs revealed that those coding for heat shock proteins were present in a translationally competent form in infected cells. Inhibition of induced gene expression in infected Drosophila cells therefore involves, but is not necessarily solely mediated by, effects at the level of translation.
果蝇细胞的小核糖核酸病毒感染抑制了热休克诱导蛋白的出现。对细胞内信使核糖核酸的检测显示,那些编码热休克蛋白的信使核糖核酸在受感染细胞中以可进行翻译的形式存在。因此,受感染果蝇细胞中诱导基因表达的抑制涉及翻译水平的影响,但不一定完全由其介导。