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苏丹儿童的乳糜泻

Coeliac disease in Sudanese children.

作者信息

Suliman G I

出版信息

Gut. 1978 Feb;19(2):121-5. doi: 10.1136/gut.19.2.121.

Abstract

Coeliac disease has not hitherto been documented in Sudanese children. This report describes seven Sudanese children with coeliac disease of whom two are siblings. They all had evidence of impaired intestinal absorption, severe histological changes of their jejunal mucosa with clinical and histological improvement on gluten free/sorgham free diet. Subsequently one patient had a clinical relapse when gluten was reintroduced; four had positive gluten challenge using serial one hour blood xylose estimation. They all belonged to the upper socioeconomic group of the society in the north of the Sudan.

摘要

乳糜泻在苏丹儿童中迄今尚无文献记载。本报告描述了7名患有乳糜泻的苏丹儿童,其中两名是兄弟姐妹。他们均有肠道吸收受损的证据,空肠黏膜有严重的组织学改变,采用无麸质/无高粱饮食后临床和组织学表现均有改善。随后,1例患者重新摄入麸质后出现临床复发;4例通过连续1小时血液木糖测定进行麸质激发试验呈阳性。他们均属于苏丹北部社会经济地位较高的群体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/200b/1411809/282bcd349465/gut00459-0046-a.jpg

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