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人类巨细胞病毒感染与慢性血精症相关。

Infection by human cytomegalovirus associated with chronic hematospermia.

作者信息

Koment R W, Poor P M

出版信息

Urology. 1983 Dec;22(6):617-21. doi: 10.1016/0090-4295(83)90309-6.

DOI:10.1016/0090-4295(83)90309-6
PMID:6316613
Abstract

Hematospermia, or blood in the ejaculate, is not an infrequent urologic condition most often occurring without recognizable physical dysfunction. It is regarded as benign and self-resolving. In its chronic form, however, it may manifest periodic recurrences or persistence for months to years. We had opportunity to follow the course of cytomegalovirus (CMV) infection in a patient experiencing both chronic hematospermia and CMV mononucleosis. The level of virus output in urine (representing systemic CMV infection) remained constant over a period of forty-four weeks during and after convalescence from the mononucleosis syndrome. However, virus isolation from semen (representing localized CMV infection) appeared to parallel the course of and concomitantly terminate with the resolution of the urologic condition. The concentration and temporal association of CMV with the course of chronic hematospermia is suggestive of a causative role in this genital pathology.

摘要

血精症,即精液中带血,是一种并不罕见的泌尿系统病症,通常在没有明显身体功能障碍的情况下出现。它被认为是良性的且可自行缓解。然而,在其慢性形式中,可能会出现周期性复发或持续数月至数年。我们有机会跟踪一名同时患有慢性血精症和巨细胞病毒(CMV)单核细胞增多症患者的CMV感染病程。在单核细胞增多症综合征康复期间及之后的44周内,尿液中的病毒排出量(代表全身性CMV感染)保持恒定。然而,从精液中分离出的病毒(代表局部CMV感染)似乎与泌尿系统病症的病程平行,并随着病症的缓解而同时终止。CMV与慢性血精症病程的浓度及时间关联表明其在这种生殖器病变中起致病作用。

相似文献

1
Infection by human cytomegalovirus associated with chronic hematospermia.人类巨细胞病毒感染与慢性血精症相关。
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2
Cytomegalovirus in the mononucleosis syndrome in children.儿童单核细胞增多症综合征中的巨细胞病毒
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引用本文的文献

1
Hematospermia: etiology, diagnosis, and treatment.血精症:病因、诊断与治疗。
Reprod Med Biol. 2011 May 10;10(3):153-159. doi: 10.1007/s12522-011-0087-4. eCollection 2011 Sep.
2
Etiologic classification, evaluation, and management of hematospermia.血精症的病因分类、评估及处理
Transl Androl Urol. 2017 Oct;6(5):959-972. doi: 10.21037/tau.2017.06.01.
3
Hematospermia: etiological and management considerations.血精症:病因及处理考量
Int Urol Nephrol. 2009;41(1):77-83. doi: 10.1007/s11255-008-9409-9. Epub 2008 Jun 19.
4
Haematospermia - a systematic review.血精症——一项系统综述
Ann R Coll Surg Engl. 2006 Jul;88(4):339-42. doi: 10.1308/003588406X114749.
5
Viruses in the mammalian male genital tract and their effects on the reproductive system.哺乳动物雄性生殖道中的病毒及其对生殖系统的影响。
Microbiol Mol Biol Rev. 2001 Jun;65(2):208-31 ; first and second pages, table of contents. doi: 10.1128/MMBR.65.2.208-231.2001.
6
Endorectal coil MR imaging findings in hemospermia.血精症的直肠内线圈磁共振成像表现
MAGMA. 1999 May;8(2):91-7. doi: 10.1007/BF02590525.
7
Refractory haemospermia: any predictive factors?难治性血精症:有哪些预测因素?
Int Urol Nephrol. 1995;27(3):335-9. doi: 10.1007/BF02564772.
8
Elimination of toxicity and enhanced cytomegalovirus detection in cell cultures inoculated with semen from patients with acquired immunodeficiency syndrome.在接种获得性免疫缺陷综合征患者精液的细胞培养物中消除毒性并增强巨细胞病毒检测
J Clin Microbiol. 1986 Oct;24(4):657-60. doi: 10.1128/jcm.24.4.657-660.1986.