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Ketoconazole treatment of nail infection in chronic mucocutaneous candidiasis.

作者信息

Roberton D M, Hosking C S

出版信息

Aust Paediatr J. 1983 Sep;19(3):178-81. doi: 10.1111/j.1440-1754.1983.tb02088.x.

DOI:10.1111/j.1440-1754.1983.tb02088.x
PMID:6316890
Abstract

Chronic mucocutaneous candidiasis is an immunodeficiency disorder which has significant morbidity due to mucous membrane, skin and nail infection. Attempts at reconstitution of immunological abnormalities have had only limited success. Ketoconazole is a newly available oral antifungal agent with activity against candida species. Prolonged administration of ketoconazole to four children with chronic mucocutaneous candidiasis caused marked improvement at infected sites. Resolution of nail infections took up to 12 months.

摘要

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